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NeuroBio Term Project – Hodgkin–Huxley Model

This repository contains the materials developed as part of a Neurobiology term project during sem 07, focused on the Hodgkin–Huxley (HH) model of neuronal action potentials and its application to understanding neuromuscular disorders.

Using the Hodgkin–Huxley framework, the project also explores the physiological basis of Myotonia and Hyperkalemic Periodic Paralysis, illustrating how alterations in ion channel dynamics can lead to pathological excitability.

Repository Structure

Presentation/

  • HH_model_ppt.pdf
    Presentation introducing the Hodgkin–Huxley model, its biological basis, and mathematical formulation, along with disease-related insights.

Report/

  • HH_brief_report.pdf
    A concise report summarizing the model, assumptions, and key results.
  • HH_model.pdf
    The final detailed report including theory, equations, simulations, and discussion of disease mechanisms.

codes/

  • HH_model.ipynb
    Jupyter notebook implementing the full Hodgkin–Huxley model to simulate neuronal action potentials.
  • HH (RC only) simple model.ipynb
    A simplified RC-circuit–based neuron model used for comparison and conceptual understanding.

This repository serves as an academic record of the theoretical study and computational simulations carried out for the term project.

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theoretical and computational study of the Hodgkin–Huxley neuron model and the analysis of Myotonia and Periodic Paralysis

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