Skip to content
@OmniBioAI

OmniBioAI

AI-native bioinformatics platform for multi-omics analysis, workflow orchestration, reproducible science, and computational biology.

🧬 OmniBioAI Studio

AI-Native Bioinformatics Platform for the Future of Computational Biology

OmniBioAI Studio is an AI-native bioinformatics platform designed to accelerate scientific discovery through intelligent automation, reproducible workflows, and scalable computational infrastructure.

It provides a unified environment for genomics, multi-omics, AI-driven biological reasoning, workflow orchestration, and reproducible computational research across local machines, HPC clusters, and cloud environments.

🚀 Built for researchers, computational scientists, and developers building the next generation of biomedical AI systems.


📊 By the Numbers

3M+ lines of code 30,000+ tests across 1,300+ test files
33 repositories 231 bioinformatics/ML plugins
1,233 container images on GHCR (1,000 ARM64 SIF + Docker) 616 workflow bundles (Nextflow, WDL, CWL, Snakemake)
36M PubMed abstracts indexed 12,110 execution, cloud, HPC, and orchestration tools

📊 Live platform metrics & health → — real-time architecture, codebase stats, and service status, not just claims.


🌐 Platform Overview

OmniBioAI connects biological data, computational workflows, AI models, and scientific knowledge into a unified ecosystem.

Biological Data
      │
      ▼
 ┌──────────────────────┐
 │  OmniBioAI Platform  │
 └──────────────────────┘
      │
 ├── 🧬 Multi-Omics Analysis
 ├── 🤖 AI Agents & Scientific Reasoning
 ├── ⚙️ Workflow Orchestration
 ├── 🐳 Containerized Execution
 ├── 🖥 HPC & Cloud Compute
 ├── 📚 Knowledge Retrieval & RAG
 ├── 🔐 Security & Governance
 └── 🔬 Reproducible Research

✨ Core Capabilities

🧬 Multi-Omics Computing

Support for modern computational biology workflows:

  • Genomics
  • Transcriptomics
  • Single-cell RNA sequencing
  • Proteomics
  • Variant analysis
  • Functional annotation
  • Biological pathway analysis
  • Knowledge-driven discovery

🤖 AI-Powered Scientific Intelligence

OmniBioAI integrates AI systems designed for biological reasoning:

  • AI-assisted workflow generation
  • Biomedical knowledge retrieval
  • Literature-aware analysis
  • Scientific hypothesis generation
  • Agent-driven computational workflows
  • Model-assisted interpretation

⚙️ Unified Workflow Execution

Execute bioinformatics pipelines across multiple environments:

  • Local workstation
  • HPC clusters
  • Slurm environments
  • Cloud batch systems
  • Containerized compute environments

616 versioned workflow bundles across:

  • Nextflow
  • WDL
  • Snakemake
  • CWL

🏗️ Platform Architecture

OmniBioAI Architecture

Unified AI-Native Bioinformatics Platform — 9-layer architecture from client access through security, observability, and development environments.


🧩 Ecosystem Repositories

🚀 Core Platform

Repository Description
omnibioai Main Django workbench + 231 plugins
omnibioai-studio Electron desktop app — orchestrates the full stack
omnibioai-control-center Platform monitoring and operational dashboard
omnibioai-workbench Plugin execution environment
omnibioai-launcher Opens registry objects in Jupyter, VS Code, and RStudio
omnibioai-sdk Python SDK client
omnibioai-utils Ecosystem automation — stack lifecycle, CI/CD, coverage reporting

⚙️ Workflow & Execution

Repository Description
omnibioai-tes Tool Execution Service for local, HPC, and cloud execution
omnibioai-toolserver FastAPI tool API
omnibioai-tool-runtime Cloud-agnostic container execution runtime
omnibioai-tool-images Bioinformatics and ML container images
omnibioai-workflow-bundles Versioned reproducible workflow packages

🤖 AI & Knowledge Systems

Repository Description
omnibioai-rag Biomedical retrieval augmented generation system
omnibioai-dev-hub AI intelligence hub with semantic retrieval
omnibioai-model-registry ML model lifecycle and provenance management

🔐 Security & Governance

Repository Description
omnibioai-auth Authentication and identity services
omnibioai-api-gateway Zero-trust API gateway
omnibioai-policy-engine RBAC/ABAC policy enforcement
omnibioai-hpc-policy-engine GPU/CPU quota governance
omnibioai-security-audit Security events and observability
omnibioai-security-sdk Shared security framework
omnibioai-iam-client Identity and access management client
omnibioai-usage-client Usage-metering event-emission SDK

💰 Billing & Operations

Repository Description
omnibioai-billing Subscription billing, invoicing, and entitlement catalog
omnibioai-db-init MySQL database initialization scripts
omnibioai-dev-docker GPU/DGX development environment image (CUDA, PyTorch)

🧪 Research Infrastructure

Repository Description
omnibioai-lims Biological sample and metadata management
omnibioai-data Reference and example datasets
omnibioai-docs Technical documentation
omnibioai-videos Tutorials and onboarding resources

🎨 Design & Frontend

Repository Description
omnibioai-design-tokens Shared design tokens and theme
omnibioai-ui Shared UI component library
omnibioai-landing Public-facing landing page

🔬 Design Principles

Reproducibility First

Every analysis should be traceable:

  • Input provenance
  • Reference versions
  • Tool versions
  • Execution environment
  • Workflow history
  • Output artifacts

AI With Scientific Guardrails

OmniBioAI follows:

✅ Deterministic execution before AI reasoning ✅ Evidence-based biological interpretation ✅ Human review for critical decisions ✅ Complete computational provenance


🛠️ Technology Stack

Backend

  • Python
  • FastAPI
  • Django
  • MySQL
  • Redis Streams

Frontend

  • React
  • TypeScript
  • Vite
  • Design systems

AI

  • Large Language Models
  • Retrieval Augmented Generation
  • Vector search
  • Knowledge graphs
  • Scientific agents

Infrastructure

  • Docker
  • Kubernetes
  • Slurm
  • Cloud batch computing

🚀 Getting Started

🌐 Website https://omnibioai.org

📊 Live Platform Stats https://control.omnibioai.org

🐙 GitHub Organization https://github.com/OmniBioAI

📦 Container Registry (1,233 images) https://github.com/orgs/OmniBioAI/packages

🤗 Hugging Face https://huggingface.co/omnibioai

📚 Documentation See the omnibioai-docs repository

🎥 Tutorials See the omnibioai-videos repository

💬 Discord https://discord.gg/Hu6vgfAFn

🐦 Twitter https://twitter.com/OmniBioAI


👨‍💻 Creator

Created by Manish Kumar

🧬 Senior Computational Scientist | 🤖 AI-Native Bioinformatics Engineer

18 years across 🇺🇸 USA, 🇶🇦 Qatar, 🇲🇾 Malaysia, 🇸🇦 Saudi Arabia, and 🇮🇳 India, building genomics and precision medicine infrastructure for research and clinical environments.

🏥 Currently at the University of Kansas Medical Center — genomics, single-cell, exome & proteomics pipelines for rare disease and translational research.

Building intelligent computational systems at the intersection of:

Biology × AI × Software Engineering × HPC


🌟 Vision

Build the operating layer where biological data, computational workflows, and artificial intelligence converge to accelerate discovery.


⭐ Star the repositories, explore the architecture, and join the future of AI-powered computational biology.

Popular repositories Loading

  1. omnibioai-studio omnibioai-studio Public

    Electron + React + Vite desktop app for OmniBioAI — provides a visual workflow builder, plugin launcher, and unified control plane for local, HPC, and cloud bioinformatics execution. Connects to th…

    JavaScript 2

  2. omnibioai-hpc-policy-engine omnibioai-hpc-policy-engine Public

    Compute-aware HPC policy and resource governance engine for OmniBioAI — enforces GPU/CPU quota limits, Slurm-aware scheduling policies, cluster access control, and zero-trust execution decisions. P…

    Python 2

  3. omnibioai-dev-docker omnibioai-dev-docker Public

    Full GPU-accelerated AI development environment for OmniBioAI — built on NVIDIA PyTorch 25.10 with CUDA, includes R, MySQL, JupyterLab, Hugging Face Transformers, and Ollama. Designed for bioinform…

    Python 1

  4. omnibioai-toolserver omnibioai-toolserver Public

    FastAPI-based ToolServer for OmniBioAI — provides validated, asynchronous execution APIs for bioinformatics tools. Accepts tool invocation requests, validates inputs against declared schemas, execu…

    Python 1

  5. omnibioai-sdk omnibioai-sdk Public

    Official Python SDK for OmniBioAI — typed client for the object registry API (list, filter, paginate, fetch by ID), notebook launch integration for JupyterLab and RStudio, and authentication helper…

    Python 1

  6. omnibioai-tool-runtime omnibioai-tool-runtime Public

    Minimal cloud-agnostic container execution runtime for the OmniBioAI Tool Execution Service — enforces a strict input/output contract for tools running on AWS Batch, Azure Batch, and Kubernetes. Ha…

    Python 1

Repositories

Showing 10 of 25 repositories

People

This organization has no public members. You must be a member to see who’s a part of this organization.

Top languages

Loading…

Most used topics

Loading…